Botulinum toxin type A (Botox) is a natural, purified protein – exotoxin produced by anaerobic bacteria Clostridium botulinum. Injected in low doses (units) into certain facial muscles causes them to relax and skin above becomes softer and without the wrinkles. Given the fact that the function of surrounding muscles is intact face retains mimics and subtle expression.
Botox is highly effective for forehead wrinkles and wrinkles around the eyes caused by normal muscle movement through life. Procedure is fairly simple and relatively painless for patient. This treatment requires extensive knowledge of anatomy of the facial muscles as well as the pharmacokinetics of the Botox solution. Clinical effect takes 3 to 7 days to become noticeable and about 14 days for full effect to be visible.
Since the blocking effect of Botox is not permanent and is eventually lost, it is necessary to repeat the treatment every 4 to 6 months. Treatment can be repeated for any number of times provided that it is done in suitable intervals in between. In most cases, the treatment is repeated every 4 months in order to maintain a youthful and fresh look.
The Botox treatment for wrinkles on the forehead was approved in 2002 by American organization Food and Drug Administration (FDA), which controls the quality and safety of food and drugs.